Figure 3
Changing practice in de novo structure determination. Depositor declarations for the method of structure determination were parsed from PDB entries beginning in 1998, the first full year for such recordings. Numbers were normalized into percentages of all de novo determinations in each year, and plotted as histograms as identified by color coding. Multiple declarations (e.g. SAD and MIR or MAD and molecular replacement) were counted for each method, but there were few such instances. The MIR numbers include MIRAS determinations and SIR includes SIRAS; ab initio numbers also include `direct methods' and related declarations. Results are based on the PDB holdings of 2 October 2012.  [article HTML]