Acta Crystallographica Section C

Crystal Structure Communications

Volume 59, Part 8 (August 2003)

Acta Cryst. (2003). C59, o467-o469 [doi:10.1107/S0108270103013258]

2-(2-Naphthyloxy)acetate derivatives. II. A new class of antiamnesic agents

S. Thamotharan, V. Parthasarathi, P. Gupta, D. P. Jindal, P. Piplani and A. Linden

Abstract: The title compounds, 4-(2-naphthyloxymethylcarbonyl)morpholine, C₁₆H₁₇NO₃, (I), and 4-methyl-1-(2-naphthyloxymethylcarbonyl)piperazine, C₁₇H₂₀N₂O₂, (II), are potential antiamnesics. The morpholine ring in (I) and the piperazine ring in (II) adopt chair conformations. In (I), the molecules are linked by weak intermolecular C-HO interactions into chains that have a graph-set motif of C(10), while in (II), the molecules are linked by weak intermolecular C-HO interactions that generate two C(7) graph-set motifs. The dihedral angle between the naphthalene moiety and the best plane through the morpholine ring is 20.62 (4)° in (I), while the naphthalene moiety is oriented nearly perpendicular to the mean plane of the piperazine ring in (II).

Formula: C₁₆H₁₇NO₃ and C₁₇H₂₀N₂O₂

Online 22 July 2003


	Structure factor file (CIF format) (183.2 kbytes) Contains datablock I

	Structure factor file (CIF format) (68.4 kbytes) Contains datablock II

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