Acta Crystallographica Section C

Crystal Structure Communications

Volume 60, Part 3 (March 2004)

Acta Cryst. (2004). C60, o186-o190 [doi:10.1107/S0108270104001489]

Racemic 5-(4-chlorophenyl)-2-methoxyindeno[1',2':2,3]pyrido[5,6-d]pyrimidine-4,6(3H,5H)-dione-dimethylformamide (1/1) and (5RS,5aSR,10bSR)-10b-hydroxy-2-methoxy-5-(4-methoxyphenyl)-5a,10b-dihydroindeno[1',2':2,3]pyrido[5,6-d]pyrimidine-4,6(3H,5H)-dione-dimethylformamide (1/1): chains of rings generated by N-HO and C-H(arene) hydrogen bonds

J. N. Low, J. Cobo, C. Cisneros, J. Quiroga and C. Glidewell

Abstract: 5-(4-Chlorophenyl)-2-methoxyindeno[1',2':2,3]pyrido[5,6-d]pyrimidine-4,6(3H,5H)-dione crystallizes as a 1:1 dimethylformamide solvate, C₂₁H₁₄ClN₃O₃·C₃H₇NO. The heterocyclic molecules contain a planar fused-ring system and they are linked by paired N-HO hydrogen bonds [HO = 1.85 Å, NO = 2.735 (4) Å and N-HO = 179°] into centrosymmetric dimers, which are themselves linked into chains by a single C-H [bold pi] (arene) hydrogen bond. 10b-Hydroxy-2-methoxy-5-(4-methoxyphenyl)-5a,10b-dihydroindeno[1',2':2,3]pyrido[5,6-d]pyrimidine-4,6(3H,5H)-dione also crystallizes as a 1:1 dimethylformamide solvate, C₂₂H₁₉N₃O₅·C₃H₇NO. The heterocyclic molecules contain a sharply folded fused-ring system and they are linked by two independent N-HO hydrogen bonds [HO = 1.92 and 2.18 Å, NO = 2.801 (2) and 3.051 (2) Å, and N-HO = 175 and 173°] into chains of rings. In both compounds, the dimethylformamide molecules are pendent from the chains, linked via N-HO and O-HO hydrogen bonds, respectively.

Formula: C₂₁H₁₄ClN₃O₃·C₃H₇NO and C₂₂H₁₉N₃O₅·C₃H₇NO

Online 10 February 2004


	Structure factor file (CIF format) (205.0 kbytes) Contains datablock I

	Structure factor file (CIF format) (259.4 kbytes) Contains datablock II

Notes:

To open or display or play some files, you may need to set your browser up to use the appropriate software. See the full list of file types for an explanation of the different file types and their related mime types and, where available links to sites from where the appropriate software may be obtained.

The download button will force most browsers to prompt for a file name to store the data on your hard disk.

Where possible, images are represented by thumbnails.