Acta Crystallographica Section C

Crystal Structure Communications

Volume 60, Part 9 (September 2004)

ga1054 scheme

Acta Cryst. (2004). C60, o671-o673 [doi:10.1107/S0108270104017457]

Structure-activity relationships in 4- and 5-androstene: 3-acetoxy-17-methyl-17-oxo-16,17-seco-5-androstene-16-carbonitrile and 17-methyl-3,17-dioxo-16,17-seco-4-androstene-16-carbonitrile

D. Lazar, O. Klisuric, S. Stankovic, K. Penov-Gasi, E. Djurendic and R. Kovacevic

Abstract: The title compounds, C₂₂H₃₁NO₃ and C₂₀H₂₇NO₂, have similar conformations except in the molecular geometry and the bonding of two of the rings. These differences lead to marked differences in the biological activities of these compounds. Molecules of both compounds are linked by weak C-HO hydrogen bonds in the crystal structures.

Formula: C₂₂H₃₁NO₃ and C₂₀H₂₇NO₂

Online 11 August 2004


	Structure factor file (CIF format) (113.3 kbytes) Contains datablock I

	Structure factor file (CIF format) (99.9 kbytes) Contains datablock II

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