Acta Crystallographica Section C

Crystal Structure Communications

Volume 63, Part 11 (November 2007)

organic compounds

fa3106 scheme

Acta Cryst. (2007). C63, o643-o645 [ doi:10.1107/S0108270107046550 ]

Quinoline derivatives: potential antiparasitic and antiviral agents

J. Sopková-de Oliveira Santos, P. Verhaeghe, J.-F. Lohier, P. Rathelot, P. Vanelle and S. Rault

Abstract: The crystal structures of closely related quinoline compounds substituted at the 2-position by a vinyl group, either including a Cl atom [2-(1-chloro-2-methylprop-1-enyl)-8-nitroquinoline, C₁₃H₁₁ClN₂O₂, (I)] or not [2-(2-methylprop-1-enyl)-8-nitroquinoline, C₁₃H₁₂N₂O₂, (II)], show an important deviation of the vinyl group from coplanarity with the quinoline ring system if the Cl atom is present. The nitro group is perpendicular [in (II)] or nearly so [in (I)] to the quinoline ring system. In (II), all non-H atoms except the nitro O atoms are located on a crystallographic mirror plane.

Formula: C₁₃H₁₁ClN₂O₂ and C₁₃H₁₂N₂O₂


	Structure factor file (CIF format) (263.4 kbytes) [ doi:10.1107/S0108270107046550/fa3106Isup2.hkl ] Contains datablock I

	Structure factor file (CIF format) (112.2 kbytes) [ doi:10.1107/S0108270107046550/fa3106IIsup3.hkl ] Contains datablock II

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