Acta Cryst. (2013). C69, 1077-1080 [ doi:10.1107/S0108270113021082 ]
Synopsis: While the crystal structure of tricyclic acyclovir dihydrate containing an (H2O)8 solvent water molecule cluster has been described previously, the disorder was incompletely modeled. In this work, the disorder model is extended and includes disorder of one tricyclic acyclovir hydroxy group across an inversion centre, leading to characterization of a concerted chain of O-HO hydrogen bonds constituting a `proton-wire' structure.
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