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Acta Cryst. (2014). C70, 416-420  [ doi:10.1107/S2053229614006111 ]

Supra­molecular structures in three thio­uracil derivatives: 5,6-tri­methyl­ene-2-sulfan­yl­idene-1,2-di­hydro­pyrimidin-4(3H)-one, 2-(4-fluorobenzyl­sulfan­yl)-5,6-tri­methyl­ene­pyrimidin-4(3H)-one and methyl 2-{[2-(4-fluoro­benzyl­sulfan­yl)-5,6-tri­methyl­ene­pyrimidin-4-yl]­oxy}acetate

Y.-J. Zhou, J. Lv, K. Yu, J.-P. Ma and D.-S. Guo

Synopsis: Three 5,6-tri­methyl­ene­pyrimidin-4-one derivatives display a combination of N-H...O, N-H...S, C-H...O and C-H...N hydrogen bonds. The study of the mol­ecular and supra­molecular structures of thio­uracil derivatives is significant in the development of lipoprotein-associated phospho­lipase A2 inhibitors.

Formula: C7H8N2OS, C14H13FN2OS and C17H17FN2O3S


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