January 2005 issue
Cover illustration: Methyl-D-erythritol-2,4-cyclodiphosphate synthase (IspF) is involved in the biosynthesis of isoprenoid precursors. Results presented in this issue by Kemp et al. (p. p. 45) and also by Ni et al. in 2004 (Acta Cryst. D60, 1949-1957) indicate that the enzyme binds geranyl and farnesyldiphosphate at the core of a trimeric assembly.