Acta Crystallographica Section D

Biological Crystallography

Volume 62, Part 8 (August 2006)


Get-Phases 2005

[Buy print version] A printed copy of this issue is available for purchase

[Preface]
[Issue Author Index][Volume Author Index]
[Cover illustration] Cover illustration: This figure illustrates the packing of the small-angle X-ray scattering (SAXS) envelope in the crystallographic unit cell of nitrite reductase. The molecular replacement solution was found with the FSEARCH program (p. 909).

research papers


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Acta Cryst. (2006). D62, 843-851  [ doi:10.1107/S0907444906024395 ]

A large-scale, high-efficiency and low-cost platform for structural genomics studies

X.-D. Su, Y. Liang, L. Li, J. Nan, E. Bröstromer, P. Liu, Y. Dong and D. Xian

Synopsis: A large-scale, cost-effective, semi-automated platform for structural genomics has been set up at Peking University and this platform is aiming at a cost of US $10 000 per structure determination.

Online 18 July 2006


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Acta Cryst. (2006). D62, 852-858  [ doi:10.1107/S0907444906014120 ]

Advanced beamline automation for biological crystallography experiments

C. Cork, J. O'Neill, J. Taylor and T. Earnest

Synopsis: Beamline automation has significantly improved the throughput and accuracy of X-ray data collection from biological molecules. Further improvements will make the systems even more robust and offer a route to optimized and remote data collection.

Online 18 July 2006


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Acta Cryst. (2006). D62, 859-866  [ doi:10.1107/S0907444906019949 ]

HKL-3000: the integration of data reduction and structure solution - from diffraction images to an initial model in minutes

W. Minor, M. Cymborowski, Z. Otwinowski and M. Chruszcz

Synopsis: An expert system for semi-automatic or automatic analysis of X-ray diffraction data has been developed and used for over 140 new structure determinations. The typical end result is an interpretable electron-density map with a partially built structure.

Online 18 July 2006


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Acta Cryst. (2006). D62, 867-876  [ doi:10.1107/S0907444906023481 ]

Estimation of anomalous signal in diffraction data

Z. Dauter

Synopsis: Various criteria used for estimation of the anomalous signal in diffraction data are discussed.

Online 18 July 2006


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Acta Cryst. (2006). D62, 877-882  [ doi:10.1107/S0907444906023547 ]

Membrane's Eleven: heavy-atom derivatives of membrane-protein crystals

J. P. Morth, T. L. Sørensen and P. Nissen

Synopsis: A database is presented of heavy-atom derivatives that have been used in structure determination of membrane proteins. Compounds of organo-mercurials, PtII and trimethyl-lead are particularly successful.

Online 18 July 2006


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Acta Cryst. (2006). D62, 883-890  [ doi:10.1107/S0907444906006445 ]

SAD phasing by OASIS-2004: case studies of dual-space fragment extension

D. Yao, S. Huang, J. Wang, Y. Gu, C. Zheng, H. Fan, N. Watanabe and I. Tanaka

Synopsis: Iterative dual-space fragment extension with protein SAD data is performed by a combination of the programs OASIS-2004, DM, RESOLVE (build only) and ARP/wARP. The procedure is beneficial to high-throughput protein structure determination.

Online 18 July 2006


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Acta Cryst. (2006). D62, 891-896  [ doi:10.1107/S0907444906010432 ]

From phasing to structure refinement in-house: Cr/Cu dual-wavelength system and a loopless free crystal-mounting method

N. Watanabe

Synopsis: Examples of Cr SAD structure solutions using a Cr/Cu dual-wavelength system in combination with a loopless free crystal-mounting method are shown.

Online 18 July 2006


 

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Acta Cryst. (2006). D62, 897-900  [ doi:10.1107/S0907444906012704 ]

Recent advances in direct phasing methods for heavy-atom substructure determination

H. Xu and H. A. Hauptman

Synopsis: Recent development on statistical direct phasing methods for heavy-atom substructure determination has been outlined.

Online 18 July 2006


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Acta Cryst. (2006). D62, 901-908  [ doi:10.1107/S0907444906008122 ]

ACORN: a review

J. X. Yao, E. J. Dodson, K. S. Wilson and M. M. Woolfson

Synopsis: ACORN has been used to solve a number of protein structures and has been extended to work with data to resolution down to 1.7 Å.

Online 18 July 2006


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Acta Cryst. (2006). D62, 909-914  [ doi:10.1107/S0907444906014089 ]

Macromolecular envelope determination and envelope-based phasing

Q. Hao

Synopsis: This paper describes the development of the FSEARCH program for locating envelopes in the unit cell and possible ways to extend phases to crystallographic data resolution.

Online 18 July 2006


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Acta Cryst. (2006). D62, 915-922  [ doi:10.1107/S0907444906017161 ]

Automated ligand fitting by core-fragment fitting and extension into density

T. C. Terwilliger, H. Klei, P. D. Adams, N. W. Moriarty and J. D. Cohn

Synopsis: An automated ligand-fitting procedure has been developed and tested on 9327 ligands and (Fo - Fc)exp(i[varphi]c) difference density from macromolecular structures in the Protein Data Bank.

Online 18 July 2006


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Acta Cryst. (2006). D62, 923-932  [ doi:10.1107/S0907444906012650 ]

Considerations for the refinement of low-resolution crystal structures

B. DeLaBarre and A. T. Brunger

Synopsis: Methods and considerations for the structure solution and refinement of the ATPase p97/VCP at 4.7 to 3.5 Å resolution are described.

Online 18 July 2006


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Acta Cryst. (2006). D62, 933-940  [ doi:10.1107/S090744490601153X ]

Structural basis for non-catalytic and catalytic activities of ribonuclease III

X. Ji

Synopsis: The crystal structures of bacterial ribonuclease III (RNase III) in complex with double-stranded (ds) RNA provide a structural basis for its non-catalytic and catalytic activities and insight into the mechanism of dsRNA processing by all members of the RNase III family.

Online 18 July 2006


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Acta Cryst. (2006). D62, 941-945  [ doi:10.1107/S0907444906008900 ]

On the complementarity of methods in structural biology

A. Liljas

Synopsis: The analysis of the translation apparatus has made it eminently clear that the complementarity of structural methods is needed to get an understandable and reasonably clear picture.

Online 18 July 2006


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