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Cover illustration: The three-component Rieske non-heme iron toluene 2,3-dioxygenase system catalyses the hydroxylation of many aromatic hydrocarbon substrates (p. 24). The system consists of a reductase, ferredoxin, and a terminal dioxygenase. The cover figure illustrates a modelled binary complex between the three-domain reductase (blue, green, orange) and ferredoxin (grey) during the initial electron transfer. Two electrons are transferred from NADH (cyan) in the hydride transfer to FAD (red) in the reductase. The ferredoxin is believed to dock between the FAD-binding domain (orange) and C-terminal domain (green) to shuttle one electron from the FAD to the active site of the dioxygenase. |
Acta Cryst. (2009). D65, 1-10 [ doi:10.1107/S0907444908029867 ]
Synopsis: An analysis of the different patterns of subunit association observed in the crystal structures of various homotetrameric proteins is presented.
Online 19 December 2008
Acta Cryst. (2009). D65, 11-17 [ doi:10.1107/S0907444908032186 ]
Synopsis: The structure of the effector domain of the influenza protein NS1, a validated antiviral drug target, has been solved in two space groups.
Online 19 December 2008
Acta Cryst. (2009). D65, 18-23 [ doi:10.1107/S0907444908035440 ]
Synopsis: Improvements to the Biomolecular Crystallization Database are described, including new search features and expanded content. A few examples of searches and analysis are given.
Online 19 December 2008
Acta Cryst. (2009). D65, 24-33 [ doi:10.1107/S0907444908036524 ]
Synopsis: The crystal structures of the three-component toluene 2,3-dioxygenase system provide a model for electron transfer among bacterial Rieske non-heme iron dioxygenases.
PDB references: 3ef6, 3dqy, 3en1 and 3eqq
Online 19 December 2008
Acta Cryst. (2009). D65, 34-40 [ doi:10.1107/S0907444908036548 ]
Synopsis: The enzyme dehaloperoxidase (DHP) from the terebellid polychaete Amphitrite ornata, which can function as both a hemoglobin and a peroxidase, has been studied.
PDB reference: 3dr9
Online 19 December 2008
Acta Cryst. (2009). D65, 41-48 [ doi:10.1107/S0907444908037256 ]
Synopsis: The crystal structure of a human carbonmonoxy hemoglobin has been determined at 2.8 Å resolution. The structure, which is in a relaxed conformation, shows rotation of
His63(E7) out of the distal pocket, creating a ligand channel to the solvent.
PDB reference: 3d17
Online 19 December 2008
Acta Cryst. (2009). D65, 49-57 [ doi:10.1107/S0907444908037451 ]
Synopsis: Crystal structures of the C-half domain of the galactose-binding lectin EW29 from the earthworm L. terrestris in complex with D-lactose and N-acetyl-D-galactosamine were determined.
Online 19 December 2008
Acta Cryst. (2009). D65, 58-66 [ doi:10.1107/S0907444908039243 ]
Synopsis: The X-ray crystal structures of the BIR3 domain of cIAP1 in complex with N-terminal peptides from SMAC and caspase-9 have been determined. The binding affinities of the complexes were determined using the surface plasmon resonance technique. The structures were compared with similar structures of XIAP.
Online 19 December 2008
Acta Cryst. (2009). D65, 67-73 [ doi:10.1107/S0907444908039486 ]
Synopsis: Structural analysis of a highly stable FGF-1 mutant based on 1.70 Å crystal structure reveals three localized conformational changes.
PDB reference: 2q9x
Online 19 December 2008
Acta Cryst. (2009). D65, 74-84 [ doi:10.1107/S0907444908039292 ]
Synopsis: The water molecules in crystal structures of bovine pancreatic phospholipase A2 have been investigated in order to identify the invariant water molecules and their possible roles in the structure and function of the enzyme.
Online 19 December 2008
Acta Cryst. (2009). D65, 85-92 [ doi:10.1107/S0907444908040195 ]
Synopsis: The atomic resolution structure of pseudoazurin from Hyphomicrobium denitrificans demonstrates that its spectroscopic properties are a consequence of its characteristic Cu coordination geometry.
PDB reference: 3ef4
Online 19 December 2008
Acta Cryst. (2009). D65, 93-95 [ doi:10.1107/S0907444908041565 ]
Synopsis: Obituary for H. C. Freeman.
Online 19 December 2008
Acta Cryst. (2009). D65, 96-100 [ doi:10.1107/S0907444908036482 ]
Online 19 December 2008
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