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A printed copy of this issue is available for purchaseActa Crystallographica Section D: Biological Crystallography
Volume 65, Part 2 (February 2009)
Copyright (c) International Union of Crystallography 2009
A printed copy of this issue is available for purchase
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Acta Cryst. (2009). D65, 101-111
[ doi:10.1107/S0907444909000778 ]
Synopsis: A case of imperfect pseudo-merohedral twinning in monoclinic crystals of fungal fatty acid synthase is discussed. A space-group transition during crystal dehydration resulted in a Moiré pattern-like interference of the twinned diffraction patterns.
Online 20 January 2009
Acta Cryst. (2009). D65, 112-120
[ doi:10.1107/S0907444908039875 ]
Synopsis: X-ray crystallographic and complementary functional studies have contributed significantly to the current understanding of gene transcription. Here, recent structure-function studies on various aspects of the elongation phase of transcription are summarized.
Online 20 January 2009
Acta Cryst. (2009). D65, 121-127
[ doi:10.1107/S0907444908040006 ]
Synopsis: Interpretation of low-resolution X-ray crystallographic data can prove to be a difficult task. The challenges faced in electron-density interpretation, the strategies that have been employed to overcome them and developments to automate the process are reviewed.
Online 20 January 2009
Acta Cryst. (2009). D65, 128-133
[ doi:10.1107/S0907444908043795 ]
Synopsis: Refinement is meaningful even at 4 Å or lower, but with present methodologies it should start from high-resolution crystal structures whenever possible.
Online 20 January 2009
Acta Cryst. (2009). D65, 134-139
[ doi:10.1107/S090744490900081X ]
Synopsis: The need for validation of macromolecular crystal structures is discussed. A general approach to validation is presented, together with examples of its implementation in the special case of macromolecular crystallography.
Online 20 January 2009
Acta Cryst. (2009). D65, 140-147
[ doi:10.1107/S0907444908041085 ]
Synopsis: A case-matched control protocol provides a useful method to compare sets of macromolecular structures.
Online 20 January 2009
Acta Cryst. (2009). D65, 148-155
[ doi:10.1107/S090744490804362X ]
Synopsis: This paper reports on the current status of structure validation in chemical crystallography.
Online 20 January 2009
Acta Cryst. (2009). D65, 156-168
[ doi:10.1107/S0907444909001905 ]
Synopsis: The article summarizes the information that is gained from and the errors that are found in carbohydrate structures in the Protein Data Bank. Validation tools that can locate these errors are described.
Online 20 January 2009
Acta Cryst. (2009). D65, 169-175
[ doi:10.1107/S0907444908020039 ]
Synopsis: In a first systematic exploration of phasing with Rosetta de novo models, it is shown that all-atom refinement of coarse-grained models significantly improves both the model quality and performance in molecular replacement with the Phaser software.
Online 20 January 2009
Acta Cryst. (2009). D65, 176-185
[ doi:10.1107/S0907444908037591 ]
Synopsis: An evaluation of validation and real-space intervention possibilities for improving existing automated (re-)refinement methods.
Online 20 January 2009
Acta Cryst. (2009). D65, 186-192
[ doi:10.1107/S0907444908036640 ]
Synopsis: The ongoing story of the structure of EmrE, the archetypical member of the small multidrug-resistance family, is described.
Online 20 January 2009
Acta Cryst. (2009). D65, 193-199
[ doi:10.1107/S0907444909001292 ]
Synopsis: An analysis is presented of the methodological errors that led to the incorrect structure of MsbA.
Online 20 January 2009