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Figure 3
Structural diagrams of lumazine synthase from BaLS. (a) Packing of three icosahedral halves in the asymmetric unit of the P21212 crystal lattice. (b) Icosahedral assembly of the enzyme. The view is along the fivefold icosahedral axis. Each pentamer is shown in a different colour and inorganic phosphate ions found in the active sites are shown as spheres. (c) Labelled secondary-structure arrangement of a monomer. (d) Structural comparison of BaLS with icosahedral LSs from B. subtilis, A. aeolicus and Spinacia oleacea; BaLS is shown in red. (e) Structural comparison of BaLS with pentameric enzymes from M. tuberculosis, Schizosaccharomyces pombe, Saccharomyces cerevisiae and Brucella abortus; BaLS is shown in red. (f) Stereodiagram of the 2|Fo| − |Fc| electron-density map around the active site of the enzyme with bound inorganic phosphate ion; the residues of a symmetry-equivalent adjacent subunit are labelled with primes.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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