Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain

Meinke, G.; Phelan, P.; Fradet-Turcotte, A.; Archambault, J.; Bullock, P.A.

doi:10.1107/S0907444911014302

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 6
(a) A ribbon diagram of the T-ag OBD triple-mutant hexamer structure looking down the sixfold axis. The different protomers are colored differently. The disulfide linkage is indicated by yellow spheres. The N-termini are labelled. A box is drawn around the region used in the close-up view. (b) A close-up of the 2F_o − F_c σ_A-weighted electron-density map contoured at 0.8σ around the protein–protein interface. Again, the different protomers are colored differently and the residues are shown as sticks and labeled. The disulfide bond is shown in yellow.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 67| Part 6| June 2011| Pages 560-567

https://doi.org/10.1107/S0907444911014302

Open

access

Follow Acta Cryst. D

Search IUCr Journals		doi		Advanced search
Author		volume	page