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Figure 5
The interactions of the trisaccharide ligand (orange) bound at the −1, −2 and −3 subsites of the protein. The key protein residues are shown in yellow and hydrogen bonds are marked by dashes. Note the site of the Ala259 mutation: the space freed by the side chain of Glu259 was occupied by the sugar unit −1, which is now in a relaxed 4C1 conformation.

Journal logoBIOLOGICAL
ISSN: 1399-0047
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