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Figure 2
Difference density map results with Fourier coefficients (F1F2)exp(iφ) based on the presence or absence of scattering contributions in the data and/or model. If neither an Fo nor an Fc contribution is present, the difference map becomes meaningless. Interpretable positive omit difference density (i.e. a difference density map calculated from the model with the ligand omitted) is therefore the primary evidence providing distinct proof for the presence of a ligand.

Journal logoBIOLOGICAL
ISSN: 1399-0047
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