Figure 5
Partially disordered ligand. The fluorescein moiety of the ligand molecule (F6Z A1356) is missing in the electron density of the thyroxine-binding globulin, PDB entry 2xn7 (Qi et al., 2011BB48), even in 0.4[sigma] noise-level 2mFo - DFc density. The 1.43 Å resolution mFo - DFc map contoured at ±3[sigma] (green/red) and 2mFo - DFc maximum-likelihood omit map contoured at 1[sigma] (blue) are shown. Maps were calculated for a refined model with the ligand atoms omitted.  [article HTML]

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