Acta Cryst. (2013). D69, 920-923 [ doi:10.1107/S0907444913002412 ]
Abstract: Crystal dehydration is a post-crystallization technique that can potentially improve the diffraction of macromolecular crystals. There are currently several ways of undertaking this process; however, dehydration experiments are often limited in their throughput and require prior manipulation of the samples. In the present study, a novel method is proposed that uses in situ plate screening to assess the effect of dehydration by combining the throughput of 96-well crystallization plates with direct X-ray feedback on crystal diffraction quality.
Keywords: high throughput; in situ plate screening; dehydration.
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