Figure 1
The proposed modification pathway of 5-oxyuridine derivatives. CmoA has been implicated in the modification of mo5U to cmo5U (Nasvall et al., 2004BB24), although this reaction involves more than the addition of a single methyl group, indicating that either additional enzymes and/or cofactors are involved. No enzymes involved in the conversion of U to ho5U or cmo5U to mcmo5U have been identified.  [article HTML]