Figure 6
Tse3-Tsi3 interactions. (a) Insertion of three loops of Tsi3 (ribbon model in cyan), including two [beta]-hairpins bridging [beta]4-[beta]5 and [beta]7-[beta]8 and a loop connecting [beta]9 and [alpha]1, into the substrate-binding groove of Tse3 (surface representation in yellow). (b) The hydrogen-bond network formed between Tse3 (yellow) and Tsi3 (cyan) around the catalytic Glu residue in Tse3. The amino acids involved in hydrogen-bond formation are represented as stick models coloured by element.  [article HTML]