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Figure 4
The proposed mechanism of action for the hydrolysis of MTA by MTANs involves the essential acidic residue in the lid of the active site and a water molecule that acts as a nucleophile which is activated by an arginine and a glutamic acid residue.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
Volume 70| Part 1| December 2014| Pages 177-185
doi:10.1107/S1399004713026655
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