 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
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![[Figure 6]](dz5326fig6mag.jpg)
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Figure 6
Location of the I141V mutation of CRMP-4 in ALS patients. (a) Ribbon presentation of the CRMP-4 tetramer. The arm–lever interface is formed by, for example, chains A and B (red and blue) and the arm–arm interface by, for example, chains A and D (red and gold). The position of the I141V mutation is indicated by grey spheres. (b) Close-up stereoview of the I141V mutation. The mutated Ile is shown in yellow stick representation, with the surrounding interacting residues in green. Mutation of Ile to Val would result in a small void in the shown hydrophobic cluster. |
![[Figure 6]](dz5326fig6.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
