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Figure 6
DEN parameter grid search for the re-refinement of full-length p97 in complex with ADP at 4.25 Å resolution. For each parameter combination 20 DEN refinement repeats were carried out. (a) The resulting Rfree values are represented in a contour plot as a function of the γ and wDEN parameters. (b) The r.m.s.d.s of the corresponding structures to the best available structure of p97 in complex with ADP (PDB entry 3cf3 ) are also shown as a contour plot. There is good agreement between the r.m.s.d. and Rfree contour plots.

Journal logoBIOLOGICAL
ISSN: 1399-0047
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