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Figure 2
Overall structure of NO66176–C complexed with Rpl8 peptide. (a) Cartoon representation of the crystal structure of NO66176–C complexed with Rpl8204–224, a peptide derived from Rpl8. The JmjC domain, the dimerization hinge domain, the β-hairpin motif and the C-terminal wHTH domain are shown in pink, cyan, orange and magenta, respectively. The Rpl8 peptide is coloured green. (b) The bound peptide Rpl8204–224 is shown as sticks. The Fo − Fc OMIT electron-density map for bound substrate was contoured at 3.0σ. A cartoon representation of the dimeric (c) and tetrameric (d) structure of NO66176–C in complex with Rpl8204–224 is shown. A dimer is present in the asymmetric unit. Two dimers related by crystallographic twofold symmetry pack against each other to form the tetramer. The filled oval indicates the twofold symmetry axis.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
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