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Figure 4
Superimposition of free (PDB entry 3rjd ; magenta) and bound (this study; green) FcγRI using D2 Cα atoms. No major conformational change can be seen upon Fc binding. However, the position of FcγRI D3, which is not involved in any interactions with Fc, FcγRI D1 or FcγRI D2, appears to depend on both crystal packing and/or the flexibility of the peptide connecting domains 2 and 3. All superimpositions were performed using LSQKAB (Kabsch, 1976BB14).

Journal logoBIOLOGICAL
ISSN: 1399-0047
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