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Figure 5
βHis97(FG4) supports the alkaline Bohr effect: βHis97(FG4) is located in the switch region of the α1:β2 interface. In T-state HuDeoxyHb (a, b), βHis97(FG4) is tightly positioned between αThr41(C6) and αPro44(CD2) and is doubly protonated. In R-state EqCNmetHb (c), βHis97(FG4) is loosely positioned between αThr38(C3) and αThr41(C6) and is singly protonated.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 72| Part 7| July 2016| Pages 892-903
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