most read articles
These are the most read articles in the last six months.
Using cryo-EM to understand the assembly pathway of respiratory complex I. (2024). Acta Cryst. D80, 159-173.
The CCP4 suite: integrative software for macromolecular crystallography. (2023). Acta Cryst. D79, 449-461.
From femtoseconds to minutes: time-resolved macromolecular crystallography at XFELs and synchrotrons. (2024). Acta Cryst. D80, 60-79.
Tomo Live: an on-the-fly reconstruction pipeline to judge data quality for cryo-electron tomography workflows. (2024). Acta Cryst. D80, 247-258.
Efficient in situ screening of and data collection from microcrystals in crystallization plates. (2024). Acta Cryst. D80, 279-288.
Putting AlphaFold models to work with phenix.process_predicted_model and ISOLDE. (2022). Acta Cryst. D78, 1303-1314.
Deep residual networks for crystallography trained on synthetic data. (2024). Acta Cryst. D80, 26-43.
A service-based approach to cryoEM facility processing pipelines at eBIC. (2024). Acta Cryst. D80, 174-180.
Neutron crystallographic refinement with REFMAC5 from the CCP4 suite. (2023). Acta Cryst. D79, 1056-1070.
Structural and functional characterization of the novel endo-α(1,4)-fucoidanase Mef1 from the marine bacterium Muricauda eckloniae. (2023). Acta Cryst. D79, 1026-1043.
STOPGAP: an open-source package for template matching, subtomogram alignment and classification. (2024). Acta Cryst. D80, https://doi.org/10.1107/S205979832400295X.
The TR-icOS setup at the ESRF: time-resolved microsecond UV–Vis absorption spectroscopy on protein crystals. (2024). Acta Cryst. D80, 16-25.
Anaerobic fixed-target serial crystallography using sandwiched silicon nitride membranes. (2023). Acta Cryst. D79, 1018-1025.
AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. (2024). Acta Cryst. D80, 270-278.
Improved joint X-ray and neutron refinement procedure in Phenix. (2023). Acta Cryst. D79, 1079-1093.
Domain structure and cross-linking in a giant adhesin from the Mobiluncus mulieris bacterium. (2023). Acta Cryst. D79, 971-979.
Advanced exploitation of unmerged reflection data during processing and refinement with autoPROC and BUSTER. (2024). Acta Cryst. D80, 148-158.
Accelerating crystal structure determination with iterative AlphaFold prediction. (2023). Acta Cryst. D79, 234-244.
Cocrystallization of ubiquitin–deubiquitinase complexes through disulfide linkage. (2023). Acta Cryst. D79, 1044-1055.
LifeSoaks: a tool for analyzing solvent channels in protein crystals and obstacles for soaking experiments. (2023). Acta Cryst. D79, 837-856.
Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography. (2023). Acta Cryst. D79, 1010-1017.
Protein model refinement for cryo-EM maps using AlphaFold2 and the DAQ score. (2023). Acta Cryst. D79, 10-21.
Raynals, an online tool for the analysis of dynamic light scattering. (2023). Acta Cryst. D79, 673-683.
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket. (2024). Acta Cryst. D80, 123-136.
Announcing the launch of Protein Data Bank China as an Associate Member of the Worldwide Protein Data Bank Partnership. (2023). Acta Cryst. D79, 792-795.
2023 update of template tables for reporting biomolecular structural modelling of small-angle scattering data. (2023). Acta Cryst. D79, 122-132.
Elucidating polymorphs of crystal structures by intensity-based hierarchical clustering analysis of multiple diffraction data sets. (2023). Acta Cryst. D79, 909-924.
Using graphlet degree vectors to predict atomic displacement parameters in protein structures. (2023). Acta Cryst. D79, 1109-1119.
Molecular-dynamics simulation methods for macromolecular crystallography. (2023). Acta Cryst. D79, 50-65.
Investigation of how gate residues in the main channel affect the catalytic activity of Scytalidium thermophilum catalase. (2024). Acta Cryst. D80, 101-112.
CCP4 Cloud for structure determination and project management in macromolecular crystallography. (2022). Acta Cryst. D78, 1079-1089.
A user-friendly plug-and-play cyclic olefin copolymer-based microfluidic chip for room-temperature, fixed-target serial crystallography. (2023). Acta Cryst. D79, 944-952.
HEIDI: an experiment-management platform enabling high-throughput fragment and compound screening. (2024). Acta Cryst. D80, https://doi.org/10.1107/S2059798324002833.
Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules. (2022). Acta Cryst. D78, 1337-1346.
Structural flexibility of Toscana virus nucleoprotein in the presence of a single-chain camelid antibody. (2024). Acta Cryst. D80, 113-122.
Time-resolved serial femtosecond crystallography on fatty-acid photodecarboxylase: lessons learned. (2022). Acta Cryst. D78, 1131-1142.
Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone. (2023). Acta Cryst. D79, 435-441.
Structural basis of regioselective tryptophan dibromination by the single-component flavin-dependent halogenase AetF. (2023). Acta Cryst. D79, 596-609.
Correcting systematic errors in diffraction data with modern scaling algorithms. (2023). Acta Cryst. D79, 796-805.
Structural features of chloroplast trigger factor determined at 2.6 Å resolution. (2022). Acta Cryst. D78, 1259-1272.
20 years of crystal hits: progress and promise in ultrahigh-throughput crystallization screening. (2023). Acta Cryst. D79, 198-205.
Analysis and validation of overall N-glycan conformation in Privateer. (2023). Acta Cryst. D79, 462-472.
MrParse: finding homologues in the PDB and the EBI AlphaFold database for molecular replacement and more. (2022). Acta Cryst. D78, 553-559.
High-resolution structure determination using high-throughput electron cryo-tomography. (2022). Acta Cryst. D78, 817-824.
Structural basis of the amidase ClbL central to the biosynthesis of the genotoxin colibactin. (2023). Acta Cryst. D79, 830-836.
Structural and functional characterization of a multi-domain GH92 α-1,2-mannosidase from Neobacillus novalis. (2023). Acta Cryst. D79, 387-400.
Correction of rhodopsin serial crystallography diffraction intensities for a lattice-translocation defect. (2023). Acta Cryst. D79, 224-233.
FLEXR: automated multi-conformer model building using electron-density map sampling. (2023). Acta Cryst. D79, 354-367.
Sequence-assignment validation in cryo-EM models with checkMySequence. (2022). Acta Cryst. D78, 806-816.
Lipidic cubic phase serial femtosecond crystallography structure of a photosynthetic reaction centre. (2022). Acta Cryst. D78, 698-708.
Scaling and merging macromolecular diffuse scattering with mdx2. (2024). Acta Cryst. D80, https://doi.org/10.1107/S2059798324002705.
Using deep-learning predictions of inter-residue distances for model validation. (2022). Acta Cryst. D78, 1412-1427.
EMinsight: a tool to capture cryoEM microscope configuration and experimental outcomes for analysis and deposition. (2024). Acta Cryst. D80, 259-269.
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. (2023). Acta Cryst. D79, 111-121.
Dependence of crystallographic atomic displacement parameters on temperature (25–150 K) for complexes of horse liver alcohol dehydrogenase. (2022). Acta Cryst. D78, 1221-1234.
Theoretical 3D electron diffraction electrostatic potential maps of proteins modeled with a multipolar pseudoatom data bank. (2022). Acta Cryst. D78, 1010-1020.
Microsecond melting and revitrification of cryo samples: protein structure and beam-induced motion. (2022). Acta Cryst. D78, 883-889.
ModelCraft: an advanced automated model-building pipeline using Buccaneer. (2022). Acta Cryst. D78, 1090-1098.
Likelihood-based signal and noise analysis for docking of models into cryo-EM maps. (2023). Acta Cryst. D79, 271-280.
A Python package based on robust statistical analysis for serial crystallography data processing. (2023). Acta Cryst. D79, 820-829.
Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris. (2023). Acta Cryst. D79, 735-745.
Exiting the tunnel of uncertainty: crystal soak to validated hit. (2022). Acta Cryst. D78, 1294-1302.
Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution. (2023). Acta Cryst. D79, 140-153.
Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. (2022). Acta Cryst. D78, 964-974.
Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases. (2023). Acta Cryst. D79, 706-720.
Verification: model-free phasing with enhanced predicted models in ARCIMBOLDO_SHREDDER. (2022). Acta Cryst. D78, 1283-1293.
Medical contrast agents as promising tools for biomacromolecular SAXS experiments. (2022). Acta Cryst. D78, 1120-1130.
Protein–macrocycle polymorphism: crystal form IV of the Ralstonia solanacearum lectin–sulfonato-calix[8]arene complex. (2023). Acta Cryst. D79, 624-631.