Acta Cryst. (2001). E57, o906-o908  [ doi:10.1107/S1600536801014222 ]

(+)-(3R)-N-Hydroxy-2-[(S)-ethoxy(4-methoxyphenyl)phosphoryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

K. Kurokawa, N. Kanehisa, M. Sawa, H. Kondo and Y. Kai

Abstract: The title compound, C₁₉H₂₃N₂O₅P, is one of two diastereomers of an arylphosphonamide hydroxamate. The absolute configuration has been determined to establish the relationship between the stereochemistry at the P atom and the activity in inhibition of matrix metalloproteinases.

Online 11 September 2001

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