Acta Cryst. (2002). E58, o1123-o1124  [ doi:10.1107/S1600536802016689 ]

A chiral 3,4-dihydro-2H-thiopyran compound

M. Evain, S. Collet and A. Guingant

Abstract: The title compound, dimethyl (3R,4S)-3-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]carbonyl}-4-dimethylamino-3,4-dihydro-2H-thiopyran-5,6-dicarboxylate, C₂₂H₂₆N₂O₇S, is the result of a diastereoselective Diels-Alder reaction between dimethyl (2E)-[(dimethylamino)methylene]-3-thiosuccinate and (4S)-3-acryloyl-4-benzyl-1,3-oxazolidin-2-one used as chiral auxiliary. Following an X-ray structure determination, the absolute configurations of both stereogenic centres formed during the cycloaddition were determined.

Online 20 September 2002

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