Acta Cryst. (2002). E58, o1395-o1396  [ doi:10.1107/S1600536802021025 ]

1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazinium chloride

C. L. Homrighausen and J. A. Krause Bauer

Abstract: The title compound, C₁₃H₁₉Cl₂N₂⁺·Cl^-, exhibits stereochemical features that are deemed necessary for 5-HT₁ subtype serotonin receptor interaction. A distance of 5.69  (1)  Å is observed between the protonated nitrogen and the centroid of the phenyl ring. The piperazine ring adopts a chair conformation and the protonated nitrogen is involved in hydrogen bonding to the chloride counter-ion. The chlorophenyl moiety is disordered, with the major conformer adopting a trans, trans geometry while the minor conformer is trans, gauche.

Online 22 November 2002

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