Acta Cryst. (2002). E58, o1460-o1462  [ doi:10.1107/S1600536802021748 ]

2(S),6(R)-Dimethyl-4-(4-methoxyphenyl)-5(R)-ethyl-3-cyclohexene-1(S)-carboxylic acid and its enantiomer: potential therapeutic agents for prostate cancer

S. Xie, Y. Hou, C. Y. Meyers and P. D. Robinson

Abstract: The synthesis, isolation, and definitive diasteriomeric characterization of the racemic title compound, C₁₈H₂₄O₃, (I), was accomplished. The two enantiomers are hydrogen bonded through their respective carboxylic acid groups, forming an octagonal bridge. A preliminary study indicates that (I) definitely inhibits prostate cancer-cell proliferation.

Online 30 November 2002

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