Acta Cryst. (2004). E60, o331-o333  [ doi:10.1107/S1600536804002077 ]

7,14-Epoxyhydrocodone-6,6-dimethoxy ketal: an unusual oxetane-containing opioid

J. R. Deschamps, A. Coop, D. A. Parrish and K. C. Rice

Abstract: The title compound, C₂₀H₂₅NO₅, which was formed by reaction of 7-bromohydrocodone-6,6-dimethoxy ketal with KO^tBu in tetrahydrofuran, is the first example of a 7,14-bridged oxetane. The geometry of the oxetane ring is consistent with previously reported structures.

Online 7 February 2004

Copyright © International Union of Crystallography
IUCr Webmaster