Acta Cryst. (2004). E60, o1215-o1216  [ doi:10.1107/S1600536804014540 ]

(3R,4S)-cis-3-Acetoxy-1-(4-methoxyphenyl)-4-(2-furanyl)azetidin-2-one

N. Anand, S. Koul, S. C. Taneja, G. N. Qazi, M. Spiteller, W. S. Sheldrick and T. Almsick

Abstract: The enantiopure title compound, C₁₆H₁₅NO₅, was obtained, together with its hydrolysed (3S,4R)-enantiomer, by resolution of racemic cis-3-acetoxy-1-(4-methoxyphenyl)-4-(2-furanyl)azetidin-2-one using a native enzyme MTCC 5125. The two H atoms on the azetidinone ring are sited in a cis configuration above the plane of the -lactam ring, as indicated by ¹H NMR.

Online 19 June 2004

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