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Acta Cryst. (2004). E60, o1571-o1572  [ doi:10.1107/S1600536804016903 ]

A novel receptor ligand: 1-(1-cyclooctylpiperidin-4-yl)indolin-2-one

D. A. Parrish, J. R. Deschamps, F. Jiang and N. T. Zaveri

Abstract: The title compound, C21H30N2O, is a member of the family of nociceptin receptor ligands derived from N-(4-piperidinyl)-2-indolinones. Modifications of the piperidine N-substituent can produce both agonists and antagonists, with the title compound being a partial agonist with high affinity. The cyclooctyl ring is disordered over two positions.

Online 21 August 2004


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