Acta Cryst. (2004). E60, o1957-o1958  [ doi:10.1107/S1600536804024304 ]

2-Fluoro-N-[7-fluoro-3,4-dihydro-2-methyl-3-oxo-4-(prop-2-ynyl)-2H-1,4-benzoxazin-6-yl]benzamide

Z.-K. Hou, C.-C. Ao, J. Song and L.-G. Chen

Abstract: The title compound, C₁₉H₁₄F₂N₂O₃, known as a protox inhibitor, was synthesized from 7-fluoro-3,4-dihydro-2-methylbenzoxazinone. The bond lengths and angles are unexceptional and the heterocyclic ring adopts a screw-boat conformation. Molecules are linked into two-dimensional layers by intermolecular C-HO hydrogen bonds, with an HO distance of 2.22  Å.

Online 9 October 2004

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