Acta Cryst. (2005). E61, o247-o249  [ doi:10.1107/S1600536804032301 ]

1-(4-Methoxyphenyl)-2-(6-methyl-2-nitro-3-pyridyloxy)propan-1-one

I. Vencato, P. H. Ferri, S. C. Santos, M. Pereira, C. Lariucci, L. I. B. Homar and H. B. Napolitano

Abstract: The title compound, C₁₆H₁₆N₂O₅, is a -ketoether derivative closely related to natural 8,4'-oxyneolignans, which are of interest because of their moderate antifungal activity against systemic mycosis. The nitro group is not coplanar with the aromatic ring, as shown by a torsion angle of 47.2 (4)°. The molecules are linked by two non-classical intermolecular C-HO hydrogen bonds with distances between donors and acceptors of 3.441 (5) and 3.539 (5) Å, leading to the formation of molecular stacking perpendicular to the bc plane.

Online 8 January 2005

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