Acta Cryst. (2005). E61, o629-o631  [ doi:10.1107/S1600536805003880 ]

(2S,4R)-1-Benzyl 2-tert-butyl 4-[N,N'-bis(tert-butyloxycarbonyl)hydrazino]-5-oxopyrrolidine-1,2-dicarboxylate

K. Kaczmarek, W. M. Wolf and J. Zabrocki

Abstract: The title compound, C₂₇H₃₉N₃O₉, is a key intermediate in the synthesis of novel -turn mimetics based on electrophilic amination of enantiomerically pure (S)-pyroglutamic acid. The molecule adopts an extended conformation which is not stabilized by either intra- or intermolecular hydrogen bonding. The pyrrolidine five-membered ring adopts an envelope conformation, with the unsubstituted C atom situated at the flap and the other four atoms almost coplanar.

Online 12 February 2005

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