Acta Cryst. (2005). E61, o536-o538  [ doi:10.1107/S160053680500228X ]

N,N'-Bis[(R)-2-hydroxy-2-phenylethyl]-N,N'-bis[(S)-1-phenylethyl]pyridine-2,6-dicarboxamide: stabilization of an asymmetric conformer through the formation of a double intramolecular hydrogen bond

M. Sosa-Rivadeneyra, L. Quintero, C. A. Parrodi, E. Juaristi and S. Bernès

Abstract: The title compound, C₃₉H₃₉N₃O₄, although having potential C₂ molecular symmetry, crystallizes as an asymmetric conformer, due to a couple of strong intramolecular hydrogen bonds involving hydroxyl groups and a pyridine N atom. This geometrical feature explains why this compound behaves as a poor chiral inductor for asymmetric synthesis.

Online 5 February 2005

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