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Acta Cryst. (2005). E61, o1810-o1811  [ doi:10.1107/S1600536805013681 ]

3-[2-(3-Chlorophenyl)ethyl]pyridine-2-carbonitrile

X.-P. Li, H.-Y. Chen, X.-M. Wang, C.-X. Zhou and Y. Zhao

Abstract: The title compound, C14H11ClN2, is the key intermediate in the synthesis of the antihistaminic drug loratadine. The benzene and pyridine rings are connected through the ethylene bridge and are coplanar. There are intermolecular [pi]-[pi] and C-Cl...N interactions and weak hydrogen bonds stabilizing the packing.

Online 21 May 2005


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