Acta Cryst. (2005). E61, o1715-o1717  [ doi:10.1107/S1600536805014303 ]

(6R,7aS)-1,3,5,6,7,7a-Hexahydro-3-(2-hydroxyphenyl)-1,1-diphenylpyrrolo[1,2-c][1,3]oxazol-6-ol

Z. Shen, Y. Ding, Y. Zhang, Y. Zhang and D.-C. Zhang

Abstract: The molecule of the title compound, C₂₄H₂₃NO₃, consists of five rings, of which the pyrrole ring and oxazole ring are not planar. The compound was designed as a catalyst of the asymmetric Baylis-Hillman reaction, but it only has poor catalysis activity. According to the crystal structure analysis, this might be caused by steric hindrance due to the intramolecular O-HN hydrogen bond. In the crystal structure, the molecules are connected by O-HO and C-HO hydrogen bonds, forming chains along [010]. The chains further interact through C-HO hydrogen bonds, stacking along [100]. In the third direction [001], there is only weak interaction, which explains the crystal habit of a thin plate.

Online 14 May 2005

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