Acta Cryst. (2005). E61, o2191-o2192  [ doi:10.1107/S160053680501843X ]

(3R,6S,7R,8R,9S,9aS)-Methyl 6,9-diacetoxy-7,8-diazidoperhydro-5-oxothiazolo[3,2-a]azepine-3-carboxylate

R. Hörger, M. Marsch, A. Geyer and K. Harms

Abstract: The absolute configuration has been determined for the bicyclic title compound, C₁₄H₁₇N₇O₇S, an intermediate in the synthesis of fixed chiral bis(1,2-aminohydroxy) compounds. In the crystal structure, the chair conformation of the seven-membered lactam ring exhibits four axial heteroatom substituents. The fused five-membered thiazolidine ring prevents inversion of the seven-membered iduronic acid ring derivative to the thermodynamically more favourable chair conformation with four equatorial substitutions.

Online 17 June 2005

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