Acta Cryst. (2005). E61, o2515-o2517  [ doi:10.1107/S1600536805022002 ]

Risperidone N-oxide hydrogen peroxide methanol solvate

K. Ravikumar, B. Sridhar, S. G. Manjunatha and S. Thomas

Abstract: In the crystal structure of the title compound {systematic name: 4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-hydroxy-1-[2-(2-methyl-4-oxo-3,4,6,7,8,9-hexahydro-2H-pyrido[1,2-a]pyrimidin-3-yl)ethyl]piperidine N-oxide hydrogen peroxide methanol solvate}, C₂₃H₂₇FN₄O₃·H₂O₂·CH₃OH, the asymmetric unit contains one molecule of risperidone N-oxide, one methanol solvent molecule and one hydrogen peroxide molecule. The piperidine ring adopts a chair conformation, while the tetrahydropyridine ring has a sofa conformation. The hydrogen peroxide molecule links the risperidone molecules to form a chain. O-HO and C-HO interactions stabilize the crystal packing.

Online 13 July 2005

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