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Acta Cryst. (2005). E61, o2573-o2575  [ doi:10.1107/S1600536805022464 ]

Hydrochlorothiazide-1,4-dioxane (1/1)

A. Johnston, A. J. Florence and A. R. Kennedy

Abstract: Hydrochlorothiazide forms a 1:1 solvate with 1,4-dioxane, C7H8ClN3O4S2·C4H8O2 [systematic name: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide-1,4-dioxane ({1/1})]. The asymmetric unit comprises one molecule of hydrochlorothiazide and halves of two solvent molecules arranged around inversion centres. The structure contains a hydrogen-bonding network comprising three N-H...O and one N-H...N hydrogen bonds.

Online 16 July 2005


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