Acta Cryst. (2005). E61, o2368-o2371 [ doi:10.1107/S1600536805020167 ]
Abstract: In the title compound, 2C14H19N4O3+·C7H3NO42-·5H2O, the asymmetric unit contains two trimethoprim cations (A and B), a dipicolinate anion and five water molecules. One of the picolinate carboxylate groups interacts with cation A via a pair of N-HO hydrogen bonds, forming a ring motif (8). A loop of O-HO hydrogen bonds is formed between four water molecules and the two carboxylate groups to form a supramolecular chain along the a axis. Molecules A and B constitute a base pair via N-HN hydrogen bonds, and these base pairs are cross-linked by N-HO and C-HO hydrogen bonds.
Online 6 July 2005
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