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Acta Cryst. (2005). E61, o3380-o3382  [ doi:10.1107/S1600536805029521 ]

6,7-Dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine ethanol disolvate

M. Xia

Abstract: The title compound, C17H14F3N3O2·2C2H5OH, was synthesized by the reaction of 4-chloro-6,7-dimethoxyquinazoline and 3-(trifluromethyl)aniline at 580 W in a domestic microwave oven and obtained in 93% yield. The bond lengths and angles are normal. Intermolecular N-H...O, O-H...N and O-H...O hydrogen bonds and [pi]-[pi] stacking interactions between the quinazoline rings of neighbouring molecules stabilize the crystal packing.

Online 21 September 2005


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