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Acta Cryst. (2007). E63, o1774-o1776  [ doi:10.1107/S1600536807011439 ]

Zolmitriptan, an antimigraine drug

K. Ravikumar, B. Sridhar and H. Krishnan

Abstract: Zolmitriptan, C16H21N3O2, a selective serotonin (5-HT) receptor agonist, is chemically designated as (S)-4-{3-[2-(dimethylamino)ethyl]-1H-indol-5-ylmethyl}oxazolidin-2-one. The molecular geometry is similar to that of sumatriptan, but the two differ in their side-chain orientations. Intermolecular N-H...O and N-H...N hydrogen bonds form a screw-symmetric helical chain along the b axis.

Online 16 March 2007


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