Acta Cryst. (2007). E63, o3942  [ doi:10.1107/S1600536807037610 ]

2-(Benzoylmethylsulfanyl)-6-benzyl-5-isopropylpyrimidin-4(3H)-one

Z.-K. Rao, S.-S. Zhang, Y.-P. He, Y.-T. Zheng and C. Li

Abstract: The title compound, C₂₂H₂₂N₂O₂S, shows remarkable activity against HIV-1. The benzoyl and benzyl rings form dihedral angles of 85.7 (2) and 77.4 (3)°, respectively, with the pyrimidine ring. The dihedral angle between the two phenyl rings is 19.3 (3)°. Intramolecular C-HN and C-HO hydrogen bonds stabilize the molecular structure. Centrosymmetrically related molecules are linked by N-HO hydrogen bonds into a dimer. In addition, intermolecular C-HO hydrogen bonds are observed

Online 1 September 2007

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