Acta Cryst. (2007). E63, o3938  [ doi:10.1107/S1600536807041803 ]

1:1 Cocrystal of (S)-3-(ammoniomethyl)-5-methylhexanoate and (S)-mandelic acid

B. Samas, W. Wang and D. B. Godrej

Abstract: The title compound, C₈H₁₇NO₂·C₈H₈O₃, exists as a complex with the base (pregabalin) in the predicted zwitterion form, based on the pK_a differences between the acid and base. The asymmetric unit consists of two molecules of each component. The -NH₃ group adopts the standard propeller conformation. The structure forms pairs of hydrophobic and hydrophilic interactions along both the a and c axes.

Online 1 September 2007

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