Poly[bis[μ-1-cyclopropyl-6-fluoro-4-oxido-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylato]nickel(II)]

In the title compound, [Ni(C17H17FN3O3)2]n, the NiII atom exists in a distorted trans-NiN2O4 octahedral geometry defined by two monodentate N-bonded and two bidentate O,O-bonded 1-cyclopropyl-6-fluoro-4-oxido-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylate (ciprofloxacinium) monoanions. The extended two-dimensional structure is a square grid. The Ni atom lies on a center of inversion.


Related literature
For the manganese, zinc and copper complexes of the ciprofloxacinium (cf) anion, see: Xiao et al. (2005); An et al. (2007). For background on the medicinal uses of Hcf, see: Mizuki et al. (1996).
The Ni(II) atom is coordinated by four oxygen atoms and two N atoms from four cf ligands (two monodentate-N and two O,O-bidentate) to form a square grid propagating approximately in the bc plane (Fig. 2).

S2. Experimental
A mixture of Ni(NO 3 ) 2 .6H 2 O (0.07 g, 0.25 mmol), ciprofloxacin hydrochloride (0.19 g, 0.5 mmol), and water (12 ml) was stirred for 30 min in air. The mixture was then transferred to a 23 ml Teflon-lined hydrothermal bomb. The bomb was kept at 433 K for 72 h under autogenous pressure. Green single crystals of the title compound suitable for X-ray analysis were obtained from the reaction mixture after cooling. Green blocks of (I) with a yield of 21%. Anal. Calc. for C 34 H 34 F 2 N 6 O 6 Ni: C 56.77, H 4.73, N 11.69%, O 13.36; Found: C 56.73, H 4.78, N 11.64%, O 13.40.

Figure 2
A view of part of a two-dimensional polymeric sheet in the crystal of the title compound showing the square-grid connectivity.

Poly[bis[µ-1-cyclopropyl-6-fluoro-4-oxido-7-(1-piperazinyl)-1,4-δihydroquinoline-3-carboxylato]nickel(II)]
Crystal data [Ni(C 17   Refinement. Refinement of F 2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F 2 , conventional R-factors R are based on F, with F set to zero for negative F 2 . The threshold expression of F 2 > σ(F 2 ) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F 2 are statistically about twice as large as those based on F, and R-factors based on ALL data will be even larger.