Acta Cryst. (2008). E64, o395-o396  [ doi:10.1107/S1600536808000251 ]

7-Hydroxyartemisinin

P. B. Carvalho, B. Liu, Y. Wu, J. S. Williamson and M. A. Avery

Abstract: Crystals of the title compound [systematic name: (3R,6R,7S,8aR,9R,12aR)-7-hydroxy-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one], C₁₅H₂₂O₆, were obtained from microbial transformation of artemisinin by a culture of Cunninghamella elegans. The stereochemistry of the compound is consistent with the spectroscopic findings in previously published works. A weak O-HO hydrogen bond occurs in the crystal structure, together with intermolecular C-HO hydrogen bonds.

Online 9 January 2008

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