Acta Cryst. (2008). E64, o704  [ doi:10.1107/S160053680800528X ]

H-D-Phe-D-Pro-Gly methyl ester hydrochloride monohydrate

M. Doi, Y. Ichimiya and A. Asano

Abstract: The conformation of the title tripeptide methyl ester hydrochloride monohydrate, 1-[2-(methoxycarbonylmethylaminocarbonyl)pyrrolidin-1-ylcarbonyl]-2-phenylethanaminium chloride monohydrate, C₁₇H₂₄N₃O₄⁺·Cl^-·H₂O, is extended, but the structure cannot be classified as any typical secondary structure. Interactions through water molecules and chloride ions were formed, in addition to peptide-peptide hydrogen bonds, stabilizing the molecular packing. In comparison with the previous -turn structure of the Phe-D-Pro-Gly analogue [Doi, Ichimiya & Asano (2007). Acta Cryst. E63, o4691], it was suggested that the difference between the chiralities of Phe and Pro residues of the title compound is important to induce the -turn structure.

Online 12 March 2008

Copyright © International Union of Crystallography
IUCr Webmaster